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Medicube Deep Vita A Retinol Serum scores 8.9/9.8 vs NIOD Copper Amino Isolate Serum 3 1:1 (CAIS3) at 7.7/9.8. Medicube Deep Vita A Retinol Serum wins for hydration.
Medicube Deep Vita A Retinol Serum takes this one, winning 2 of 5 attributes.
Scores last verified: April 2026
48 unique
5 in common
16 unique
Where Medicube Deep Vita A Retinol Serum really shines is hydration efficacy, scoring 9.8 compared to NIOD Copper Amino Isolate Serum 3 1:1 (CAIS3)'s 4.8. With Dipropylene Glycol, Butylene Glycol, and Glycerin in its top ingredients, Medicube Deep Vita A Retinol Serum delivers stronger moisture-binding capability.
Active Ingredient Strength is another area of separation. NIOD Copper Amino Isolate Serum 3 1:1 (CAIS3) scores 7.7 here versus 6.7 for Medicube Deep Vita A Retinol Serum. That difference comes down to how each formula is built — the ingredient list tells the story.
Medicube Deep Vita A Retinol Serum brings Niacinamide, Allantoin, and Dipotassium Glycyrrhizate as actives, while nIOD Copper Amino Isolate Serum 3 1:1 (CAIS3) relies on Acetyl Tetrapeptide-2. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Medicube Deep Vita A Retinol Serum is better if you have
NIOD Copper Amino Isolate Serum 3 1:1 (CAIS3) is better if you have
Medicube Deep Vita A Retinol Serum wins this comparison with a meaningfully stronger ingredient profile and overall score.
Based on ingredient analysis, Medicube Deep Vita A Retinol Serum scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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