✶

IOPE IOPE Retinol Ex… vs Medicube Hyaluronic… — Which Is Better? | Gracie

Products
Ingredients
Brands
K-Beauty
Blog
How We Score

Gracie
/Compare
/IOPE IOPE Retinol Expert 0.1%
/vs
/Medicube Hyaluronic Multi Peptide PDRN Serum

IOPE IOPE Retinol Expert 0.1% vs Medicube Hyaluronic Multi Peptide PDRN Serum

Medicube Hyaluronic Multi Peptide PDRN Serum scores 9.0/9.8 vs IOPE IOPE Retinol Expert 0.1% at 7.9/9.8. Medicube Hyaluronic Multi Peptide PDRN Serum wins for hydration.

Head to head

IOPE

IOPE Retinol Expert 0.1%

serumpremium

7.9

Buy at Olive Young

Compare

Best Moisturisers
Best Serums
Best Cleansers
Best SPF

Ingredients

Niacinamide
Retinol
Hyaluronic Acid
Salicylic Acid

K-Beauty

K-Beauty Hub
K-Beauty Moisturisers
K-Beauty Serums
K-Beauty Sunscreens

About

Methodology
About Us
All Brands
All Products

Gracie

Honest skincare intel. No jargon, no gatekeeping — just the ingredients decoded.

Medicube

Hyaluronic Multi Peptide PDRN Serum

serum

9.0

Score comparison

Medicube Hyaluronic Multi Peptide PDRN Serum takes this one, winning 2 of 5 attributes.

IOPE wins 0

Tied 3

Medicube wins 2

9.0

IOPE

Medicube

Ingredient face-off

25% overlap

15IOPE

10Shared

40Medicube

Only in IOPE IOPE Retinol Expert 0.1%

5 unique

Retinol Retinyl Palmitate Ceramide Np Carbomer Arginine

Shared ingredients

10 in common

Water Glycerin Butylene Glycol Niacinamide 2-Hexanediol Sodium Hyaluronate Adenosine Panthenol Allantoin Ethylhexylglycerin

Only in Medicube Hyaluronic Multi Peptide PDRN Serum

30 unique

Propanediol Trehalose Glyceryl Glucoside Sorbitol Sodium Chloride Disodium Edta Glucose Melia Azadirachta Leaf Extract Melia Azadirachta Flower Extract Alpha-Arbutin+20 more

Why Medicube Hyaluronic Multi Peptide PDRN Serum comes out ahead

Where Medicube Hyaluronic Multi Peptide PDRN Serum really shines is hydration efficacy, scoring 9.8 compared to IOPE IOPE Retinol Expert 0.1%'s 6.3. With Glycerin, Trehalose, and Sorbitol in its top ingredients, Medicube Hyaluronic Multi Peptide PDRN Serum delivers stronger moisture-binding capability.

Ingredient Transparency is another area of separation. Medicube Hyaluronic Multi Peptide PDRN Serum scores 8.8 here versus 7.8 for IOPE IOPE Retinol Expert 0.1%. That difference comes down to how each formula is built — the ingredient list tells the story.

Medicube Hyaluronic Multi Peptide PDRN Serum brings Niacinamide, Allantoin, and Adenosine as actives, while iOPE IOPE Retinol Expert 0.1% relies on Niacinamide, Retinol, and Retinyl Palmitate. Both approaches have merit, but the positioning and supporting ingredients make the difference.

Best for your skin type

IOPE IOPE Retinol Expert 0.1% is better if you have

Sensitive skin — the low-irritation formula keeps things gentle
Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Anyone who prefers clean, well-vetted formulations

Medicube Hyaluronic Multi Peptide PDRN Serum is better if you have

Sensitive skin — the low-irritation formula keeps things gentle
Dry or dehydrated skin that craves moisture, thanks to Glycerin
Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting

Value comparison

IOPE IOPE Retinol Expert 0.1% comes in at premium pricing with a 7.9 score, which is solid value at that tier.

Our verdict

✶ Our verdict

+1.1 lead

Medicube Hyaluronic Multi Peptide PDRN Serum wins this comparison with a meaningfully stronger ingredient profile and overall score.

7.9IOPE

9.0Medicube

Frequently asked questions

Which is better: IOPE IOPE Retinol Expert 0.1% or Medicube Hyaluronic Multi Peptide PDRN Serum?

Based on ingredient analysis, Medicube Hyaluronic Multi Peptide PDRN Serum scores higher overall. See the full score breakdown above for details on each attribute.

Do IOPE IOPE Retinol Expert 0.1% and Medicube Hyaluronic Multi Peptide PDRN Serum share ingredients?

Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.

What's the main difference between IOPE IOPE Retinol Expert 0.1% and Medicube Hyaluronic Multi Peptide PDRN Serum?

The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.

Full analysis: IOPE IOPE Retinol Expert 0.1%→Full analysis: Medicube Hyaluronic Multi Peptide PDRN Serum→

We may earn a commission from purchases made through our links, at no extra cost to you. This helps us keep Gracie free and independent.

Some links on this site are affiliate links. We may earn a commission from purchases made through our links, at no extra cost to you. This helps us keep Gracie free and independent.