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Medicube Hyaluronic Multi Peptide PDRN Serum scores 9.0/9.8 vs the ordinary Retinol 0.5% in Squalane at 6.2/9.8. Medicube Hyaluronic Multi Peptide PDRN Serum wins for hydration.
Medicube Hyaluronic Multi Peptide PDRN Serum takes this one, winning 3 of 5 attributes.
Scores last verified: April 2026
39 unique
8 unique
Where Medicube Hyaluronic Multi Peptide PDRN Serum really shines is hydration efficacy, scoring 9.8 compared to the ordinary Retinol 0.5% in Squalane's 3.8. With Glycerin, Trehalose, and Sorbitol in its top ingredients, Medicube Hyaluronic Multi Peptide PDRN Serum delivers stronger moisture-binding capability.
Active Ingredient Strength is another area of separation. Medicube Hyaluronic Multi Peptide PDRN Serum scores 7.5 here versus 3.4 for the ordinary Retinol 0.5% in Squalane. That difference comes down to how each formula is built — the ingredient list tells the story.
Medicube Hyaluronic Multi Peptide PDRN Serum brings Niacinamide, Allantoin, and Adenosine as actives, while the ordinary Retinol 0.5% in Squalane relies on Retinol, Solanum Lycopersicum (Tomato) Fruit Extract, and Rosmarinus Officinalis (Rosemary) Leaf Extract. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Medicube Hyaluronic Multi Peptide PDRN Serum is better if you have
the ordinary Retinol 0.5% in Squalane is better if you have
the ordinary Retinol 0.5% in Squalane comes in at budget pricing with a 6.2 score, which is reasonable for what you get.
Medicube Hyaluronic Multi Peptide PDRN Serum wins this comparison with a meaningfully stronger ingredient profile and overall score.
Based on ingredient analysis, Medicube Hyaluronic Multi Peptide PDRN Serum scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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© 2026 Gracie. All rights reserved. Data sourced from Open Beauty Facts (ODbL) and EU CosIng.